Adenomatous Polyposis Coli

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Also Known As:

Familial Adenomatous Polyposis; Adenomatous Polyposis of the Colon; Adenomatous Polyposis Coli, Familial; Familial Adenomatous Polyposis Coli; Familial Adenomatous Polyposis of the Colon; Familial Intestinal Polyposis; Familial Multiple Polyposi; Familial Multiple Polyposis; Familial Multiple Polyposis Syndrome; Familial Polyposis Coli; Familial Polyposis Syndrome; Familial Polyposis of the Colon; Hereditary Polyposis Coli; Myh-Associated Polyposis; Polyposis Coli; Polyposis, Adenomatous Intestinal; Adenomatous Intestinal Polyposes; Adenomatous Intestinal Polyposis; Adenomatous Polyposes, Familial; Adenomatous Polyposis Colus; Adenomatous Polyposis, Familial; Coli, Adenomatous Polyposis; Coli, Familial Polyposis; Coli, Hereditary Polyposis; Coli, Polyposis; Colus, Adenomatous Polyposis; Colus, Familial Polyposis; Colus, Hereditary Polyposis; Colus, Polyposis; Familial Adenomatous Polyposes; Familial Intestinal Polyposes; Familial Multiple Polyposes; Familial Multiple Polyposus; Familial Polyposis Colus; Familial Polyposis Syndromes; Hereditary Polyposis Colus; Intestinal Polyposes, Familial; Intestinal Polyposis, Adenomatous; Intestinal Polyposis, Familial; Multiple Polyposes, Familial; Multiple Polyposi, Familial; Multiple Polyposis, Familial; Multiple Polyposus, Familial; Myh Associated Polyposis; Myh-Associated Polyposes; Polyposes, Familial Adenomatous; Polyposes, Familial Multiple; Polyposes, Myh-Associated; Polyposi, Familial Multiple; Polyposis Coli, Adenomatous; Polyposis Coli, Hereditary; Polyposis Colus; Polyposis Colus, Adenomatous; Polyposis Colus, Familial; Polyposis Colus, Hereditary; Polyposis, Familial Adenomatous; Polyposis, Familial Multiple; Polyposis, Myh-Associated; Polyposus, Familial Multiple; Polyposis Coli, Familial; Polyposis Syndrome, Familial

Neoplasms: 1361496
- Hereditary Neoplastic Syndromes: 115
  - Adenomatous Polyposis Coli: 3472
- Neoplasms by Site: 4
  - Digestive System Neoplasms: 251
    - Gastrointestinal Neoplasms: 4515
      - Intestinal Neoplasms: 529
        Colorectal Neoplasms: 76245
        Adenomatous Polyposis Coli: 3472
- Neoplasms by Histologic Type: 2
  - Glandular and Epithelial Neoplasms: 445
    - Adenoma: 20941
      - Adenomatous Polyps: 768
        Adenomatous Polyposis Coli: 3472
Digestive System Diseases: 1068
- Gastrointestinal Diseases: 6062
  - Gastrointestinal Neoplasms: 4515
    - Intestinal Neoplasms: 529
      - Colorectal Neoplasms: 76245
        Adenomatous Polyposis Coli: 3472
  - Intestinal Diseases: 1640
    - Intestinal Neoplasms: 529
      - Colorectal Neoplasms: 76245
        Adenomatous Polyposis Coli: 3472
    - Colonic Diseases: 360
      - Colorectal Neoplasms: 76245
        Adenomatous Polyposis Coli: 3472
    - Intestinal Polyposis: 139
      - Adenomatous Polyposis Coli: 3472
- Digestive System Neoplasms: 251
  - Gastrointestinal Neoplasms: 4515
    - Intestinal Neoplasms: 529
      - Colorectal Neoplasms: 76245
        Adenomatous Polyposis Coli: 3472
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 960
- Inborn Genetic Diseases: 12342
  - Hereditary Neoplastic Syndromes: 115
    - Adenomatous Polyposis Coli: 3472

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Disease

Drug/Important Bio-Agent (IBA)